Lesson 5:
Circulatory / Endocrine System
Body Systems Exam Thursday, 2/5 - Lessons 1-7
Lesson 5:
Circulatory / Endocrine System
Learning Intention:
Explore the endocrine and circulatory system through texts and practice creating constructed responses using our graphic organizer.
Success Criteria:
I am successful when I can...
Analyze and judge student responses to past regents questions.
Engage in clichés about teenage behavior by discussing with peers.
Explore the endocrine system by actively reading an article and creating annotations.
Explain the endocrine system is vital to new real-world medications, such as Ozempic.
Elaborate by applying my knowledge of the endocrine system to regents-esque questions about Ozempic.
Standards:
HS-LS1-2.
Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
Reminders:
Practice Regents #1 due Monday 2/2
Part 1
Warm-Up
(10 min)
A patient experiences fatigue and weight loss over several months. Medical testing shows that food is mechanically broken down in the mouth and chemically digested in the stomach. Enzymes involved in digestion are present in normal amounts, and food molecules are broken into smaller units in the digestive tract.
Examination of the small intestine shows damage to the inner lining. The surface of the intestine appears smoother than normal, with fewer finger-like projections. Blood samples taken after meals show lower-than-expected levels of glucose and amino acids.
Despite normal digestion, fewer nutrients enter the bloodstream. As a result, cells throughout the body do not receive sufficient materials needed for energy and normal cellular processes.
Identify the structure in the small intestine that is damaged in this patient and state its normal function.
Explain why the patient may experience fatigue even though digestion is occurring normally.
What structure in the lungs has a similar role to villi in the small intestines? Explain how they are similar and how they both help provide energy.
SHORT RESPONSE CHECKLIST:
1) Simplify questions to figure out what is being asked.
2) Break single question into parts.
3) Number Answers - Example
1)
2)
4) Word Association Game:
Create vocabulary list of words in the margin that should be used in the response
Part 2
Circulatory System
Stop n' Jot
(5 min)
Purpose: The circulatory system’s main purpose is to transport oxygen, nutrients, and other materials to cells and carry wastes away, while working closely with other systems such as the respiratory system to pick up oxygen, the digestive system to absorb nutrients, and the excretory system to remove wastes.
The heart acts as a pump that pushes blood throughout the body.
Arteries carry blood away from the heart to different parts of the body.
Veins return blood back to the heart.
Capillaries are tiny blood vessels where oxygen, nutrients, and wastes move between the blood and body cells.
Part 3
Active Reading
Endocrine System
(10 min)
We know that teenagers may act wildly because of raging hormones, but that is not the only thing hormones do. They help control a lot of processes in our bodies by acting as messengers. Lets find out more about these amazing hormones.
Directions:
1) Actively read one of the resources below.
2) Write five (5) annotations as you read.
To stay alive, your body needs to stay balanced. This state of balance is called homeostasis. Your body has two ways to send messages to keep this balance. The nervous system sends fast electrical signals, like a text message. The endocrine system is different. It uses chemical messengers called hormones.
Hormones are made by organs called glands. These glands drop hormones directly into your bloodstream. Your blood acts like a highway, carrying these chemical packages all over your body. Hormones are slower than nerve signals, but their effects last longer. They control big jobs like growing, using energy, and reproduction.
Hormones travel everywhere in your blood, but they don't talk to every cell. They are very picky. They only work on specific "target cells." This happens because of receptor molecules on the outside of the cell.
Think of this like a Lock and Key.
The hormone is the key.
The receptor is the lock.
A hormone has a specific shape. If its shape matches the receptor’s shape, the "door" opens and the cell gets the message. If the shape doesn't match, the cell ignores it. This is why a hormone sent from your brain to your legs doesn't confuse your stomach.
One of the most important jobs of the endocrine system is controlling blood sugar. The pancreas makes a hormone called insulin. When you eat, sugar goes into your blood. The pancreas sees this and releases insulin. Insulin tells your cells to soak up the sugar for energy. This brings your blood sugar back down to normal.
Sometimes, a person's body cannot make enough insulin. Other times, their receptors (the "locks") stop working. When this happens, blood sugar stays too high. This causes a disease called diabetes.
The endocrine system also controls how you grow. The pituitary gland is in your brain. It is often called the "master gland." It releases Human Growth Hormone (HGH). This hormone tells your muscle and bone cells to divide and grow. This is what causes growth spurts when you are a teenager. If the pituitary gland makes too much or too little of this hormone, it can cause problems with a person's height.
As you grow up, the endocrine system controls reproduction. The reproductive glands—testes in males and ovaries in females—make sex hormones.
Males produce testosterone.
Females produce estrogen and progesterone.
These hormones cause changes during puberty, like a deeper voice or body hair. They also help the body make reproductive cells (sperm and eggs) so the human species can continue.
Part 4
Stop n' Jot
(5 min)
Purpose:
Glands secrete (release) hormones
Hormones are chemical messengers that travel through the blood to "target" cells and tell them to do something specific.
Hormones affect metabolism, growth, development, emotions, fertility, sexual function, sleep and blood pressure.
Hormones only work on target cells if they have the complimentary shaped receptor (Lock and Key Model)
Glands and Hormones you need to know:
1) Ovaries secrete estrogen
2) Testes secrete testosterone
3) Pancreas secretes insulin
Part 5
Turn n' Talk
(2 min)
Have you heard about a new medicine called Ozempic?
What does it do and how do you think it works?
(hint: hormones)
Part 5
Explicit Instruction
(5 min)
After a meal, nutrients enter the bloodstream as food is digested and absorbed in the small intestine. Blood glucose levels begin to rise as carbohydrates are broken down into simple sugars that move into the circulatory system. Specialized cells in the digestive tract detect these changes and release chemical signals that travel through the body.
One of these signals is GLP-1, a hormone released by cells in the small intestine shortly after eating. Once released, GLP-1 enters the bloodstream and is transported to multiple organs. These organs respond differently depending on the receptors present on their cells.
As GLP-1 circulates, it influences the activity of the pancreas. The pancreas responds by adjusting the release of substances, such as insulin, that lower blood glucose levels. At the same time, GLP-1 slows the movement of food from the stomach into the small intestine, which affects how quickly nutrients, such as glucose, enter the bloodstream.
1) Explain why GLP-1 binds only to certain receptors in the body and describe what would most likely happen to blood glucose regulation if the structure of GLP-1 were modified so that it could no longer bind to those receptors.
Step#1: Re-write the question in simpler language:
Step #2: Create a list of words you can use in your answer:
Step #3:
Break the question into parts.
Number answer lines.
Answer all parts using vocabulary.