Lesson #14:
Enzymes
Embedded Files
EOU Exam on Thursday, May 1st
Learning Intention:
Apply knowledge of enzymes (biological catalysts) to real world problems and new scenarios.
Success Criteria:
Review organic molecules by answering regents questions.
(DOK 1)
Discuss a real world example of how enzymes are used to break down organic molecules.
(DOK 2)
Derive key concept (lock and key model) from a hands-on card sort model.
(DOK 3)
Students will provide feedback in the form of a glow and grow
(DOK 4)
Reminders
Test tomorrow 10/25
Tutoring today 2-4 pm in A-301
MP 1 ends November 8th
Standard
NGSS: HS-LS1-6.
Construct and revise an explanation based on evidence from a variety of sources for how carbon, hydrogen, and oxygen from sugar molecules may combine with other elements such as nitrogen, sulfur, and phosphorus to form amino acids and other carbon-based molecules.
Part 1
Biomolecule Warm-Up Review
(sc1)
(5 min)
🥿Ballet 🩰
🥿Ballet 🩰
🎺Jazz 🎷
🎺Jazz 🎷
🎤Hip-Hop🎤
🎤Hip-Hop🎤
Part 2
Turn n' Talk Numero Uno
(sc2)
(10 min)
Mr.Pinho and Ms. Angarola
Go To White Castle:
They decide to have a burger eating contest. Believe it or not, Mr. Pinho only ate 7 burgers and Ms. Angarola on the other hand ate 22 🤯
Unfortunately, Ms. Angarola and Mr. Pinho are super messy eaters and they BOTH got food and grease all over their shirts!! Mr. Pinho and Ms. Angarola both washed their shirts and brought them in today.
Directions: View the shirts at the front of the room.
Discuss what you SEE, THINK and WONDER with your group.
(Hint: Stains are from food. Food is made up of organic molecules)
Part 3
Student Discovery:
What breaks down organic molecules?
(sc3)
(10 min)
Ketchup 🍅 and grease stains are made of organic molecules, just like all foods.
To clean their shirts, Mr. Pinho and Ms. Angarola first need to break down the organic molecules in the stains. How will we break down these molecules?
Directions
Step 1) Use the resources below in order to figure out how we can break down the organic molecules that make up Mr. Pinho' stain.
Step 2) Once you figure it out, answer the AI questions by clicking on the image below:
Part 4
Stop n'Jot (sc3)
(2 min)
Enzymes aka Organic Catalyst:
Enzymes are a type of protein that help break down macromolecules.
Substrate:
The thing the enzyme is working on.
Example: The enzyme broke the carbohydrate substrate down into glucose.
Break Down:
Turn a substrate from a macromolecule (big molecule) into a smaller molecule.
Part 5
Turn n' Talk Numero Dos
(5 min)
Directions: Let's go back to helping Mr. Pinho clean his white castle stained shirt. Turn and talk with your group and discuss what Mr. Pinho can use to break down his shirt stains. As you talk, use our new academic vocabulary:
Enzyme
Substrate
Breaking down
Macromolecule
Carbohydrates
Fats
Proteins
Building Blocks
Part 6
Turn and Talk #3
Hands-On Model
(5 min)
In a human cell, there are around 1300 specific types of enzymes.
Question:
To clean Mr. Pinho's stain, do we need to use a specific type of enzyme or will any enzyme work?
Directions: We are going to use hands-on enzyme models to try to figure out if enzymes only work on specific substrates. Use the 3d printed enzymes and substrates at your desk to try to figure out if enzymes can only attach to certain substrates.
Key Concept:
Key Concept:
Enzymes can only work on substrates that have a complimentary (matching) shape. If the substate cannot fit into the enzyme, the enzyme cannot work on it. Scientists call this a lock and key model.
Part 7:
Application to New Scenarios
Directions: In your notebooks, answer the questions below. Use the academic vocabulary in your short response answers.
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