Science - Lesson #7: Transplants

Lesson #7:

Organ Transplants,

Rejections

Immunosuppressants

Learning Intention:

Explain why organ transplants are sometimes rejected by our immune system and the role of immunosupressants.

Success Criteria:

Describe how the immune system recognizes antigens by their shape.
Explain why someone who receives an organ transplant requires immunosuppressant drugs.
Apply my knowledge of the immune system to practice questions regarding organ transplants.

Standards:

HS-LS1-2: Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.

Reminders:

Exam Thursday February 13th
Practice Regents #2 due tomorrow
Tutoring Thursdays 2-4 pm in A-301

Organ Transplants and Immunosuppressants.wav

Blood Transfusion Review

Turn n' ChatGPT

(5 min)

Directions:

Tell the AI everything you know about blood transfusions and blood types.

SchoolAIAI-Powered Tutors and Learning Activities

Part 2:

Slow Reveal Graph

(8 min)

New Slow Reveal: Organ Transplants

Discuss!

Because of the long organ donor waitlist, Maria has decided to go ahead with her pig kidney surgery, also known as xenotransplantation.

Question:

Do you think that xenotransplantation can be the solution to reducing the organ donor waitlist?

What are some issues with xenotransplantation?

Part 3:

and Unseen

(10 min)

Directions:

Step 1) Actively read the article.

Step 2) Write THREE (3) Annotations as you read:

A) ONE (1) Connection to Life

B) ONE (1) Question you have

C) ONE (1) Main Idea Summarized

Step 3) After you have read and annotated, choose ONE of the TWO questions below to answer:

Organ Transplant Article

Search Question

What is the purpose of giving organ transplant patients immunosuppressants? What is the problem with long-term use of immunosuppressants?

Unseen Question

Explain why scientists need to genetically modify pig organs before using them for human transplants. What about the antigens do scientists specifically modify and why?

Part 3:

TN'T Times THREE

(10 min)

Turn n' Talk

Número Uno

Do you think organs can be transplanted from animals into humans? Why / Why not?

Turn n' Talk

Número Dos

Do you think organs can be transplanted from animals into humans? Why / Why not?

Explain using the vocabulary to the right!

Tier 2

General Vocab

Reject

Recognize

Replace

Mistakenly

Attack

Modify / Change

Tier 3

Content Specific Vocab

Immune System

Antibodies

Antigens

Organ Rejection

Immunosuppressants

Genetically Modify

Xenotransplantation

Turn n' Talk

Número Tres

Do you think organs can be transplanted from animals into humans? Why / Why not?

Create three sentences with your group using the conjunctions

BECAUSE

BUT

Remember to the vocabulary to the right in your conjunction sentences.

Tier 2

General Vocab

Reject

Recognize

Replace

Mistakenly

Attack

Modify / Change

Tier 3

Content Specific Vocab

Immune System

Antibodies

Antigens

Organ Rejection

Immunosuppressants

Genetically Modify

Xenotransplantation

Part 5

Stop n' Jot

(3 min)

Key Concepts:

1) All cells have antigens on the surface. They are like the face of the cell.

2)The immune system looks at the antigen and determines if it belongs or a foreign threat. If the immune system determines the cells of a transplanted organ are foreign, it starts attacking the organ. This is called organ rejection.

3) Organ rejection can be reduced by the use of immunosuppressants - drugs that make the immune system calm down.

Part 6:

Exit Ticket

(5 min)

Ballet

Jazz

Hip-Hop

Question #1

Question #2

Question #3

Student Response #1

Carrying capacity is the measure of how many babies are born at any given time of the year for a specific animal population.

Student Response #2

The shape of the hormone determines what cell receptor it can attach to. If this shape were to change the hormone would not send the necessary message to the cell.

Student Response #3

Photosynthesis stores the suns energy in glucose. Animals eat this glucose and transfer the energy up the food web. Without photosynthesis, animals would have no energy and would not survive.