Lesson #3:
Antibody / Antigen
Embedded Files
EOU Exam on Thursday, May 1st
Learning Intention:
Learning Intention:
Students will be able to model how antibodies protect us from disease through the antibody antigen reaction.
Success Criteria:
Success Criteria:
I am successful when I can...
Identify how the immune system protects us from disease
Explain how the antibody-antigen reaction is specific
Model how antibodies connect to antigens depending upon shape.
Agenda:
Agenda:
1) Warm-Up
2) Mini-Lesson
3) Activity
4) Exit Ticket
Reminders:
Reminders:
Vocab Quiz on Thursday February 6th
Practice Regents #2 due Wednesday 2/12
Antibody-Antigen Reaction_ A Science Lesson.wavPart 1
Warm-Up
(5 min)
As you know, doctors are considering giving Maria Lopez a pig kidney to replace her nonfunctional kidneys. Maria's kidneys were badly damaged when she became infected by Malaria as a baby. Malaria is a parasite that is transmitted by mosquitos. Malaria can damage the kidneys by causing inflammation and impairing blood flow. This can lead to acute kidney injury (AKI) and chronic kidney disease.
Directions: On the right hand page of the medical journal, describe in your own words how Maria's body fought off the parasite. Be sure to mention the immune systems different levels of defense. Start with the first line of defense: the skin. (4 sentence minimum)
Part #2
Cengage Active Reading
(10 min)
Directions: Actively read these two paragraphs. Make THREE (3) annotations.
1 Connection between the text and your life experiences
1 Main Idea paraphrased in your own words
1 Question related to the content
Part 3
Turn and Talk Numero Uno
(2 min)
On Friday, we learned that antibodies fight pathogens.
1) Turn n' talk, can any antibody fight any pathogen?
2) Do they have to be specific?
Turn and Talk Numero Dos
(2 min)
Describe how antibodies fight specific pathogens?
Be as specific and detailed as possible!
Tier 2
Specific
Shape
Bind
Deactivate
Tier 3
Lock and Key
Protein
Antigen
Antibody
Pathogen
White Blood Cell
Turn n' Talk
Numero Tres
(5 min)
Use the conjunctions because, but and so to describe how antibodies fight specific pathogens?
Because = Cause and Effect
But = Difference
So = Consequence
Sentence Stems:
1) Antibodies can target specific pathogens because...
2) Antibodies neutralize pathogens, but...
3) Antibodies bind to a pathogen’s surface, so...
Part 4
Exit Ticket
(10 minutes)
Directions: Open the below space and explain to the AI in detail why Maria won't get as sick the second time she gets Malaria.
Part 5
Stop n' Jot
Take-away
(3 minutes)
Pathogen - foreign substance that enters the body and causes disease.
Antigen - mark on a foreign substance that indicates whether it belongs or does not belong in the body.
Antibody - attaches to antigen, either directly or indirectly destroys the pathogen.
Immune system - consists of white blood cells which fight disease.
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